In the following sections, we’ll outline gene-based approaches that may help you deal with eczema. Read on to find out what you can do to manage this condition.
The below strategies are not meant to replace your standard medical treatment. Make sure to consult with your doctor before making any significant changes to your day-to-day routine.
FLG & OVOL1
Probiotics
Treatment of a reconstructed human skin cell model with L. rhamnosus significantly increased the production of filaggrin. Similarly, L. plantarum supplements were found to increase filaggrin production in rat and mouse models of eczema [R, R].
In people with eczema, supplementation with different probiotic strains slightly improved skin inflammation. The most common Lactobacillus species tested include L. rhamnosus, L.reuteri, L. plantarum, L. paracasei, L. fermentum, and L. sakei [R, R, R, R, R, R, R, R].
Bifidobacterium species such as B. animalis, B. breve, and B. longum have been mainly tested in combination with Lactobacillus strains. The studies produced mixed results, possibly due to differences in the strains used [R, R, R, R, R, R].
Preventive prenatal maternal or postnatal pediatric supplementation with combinations of some of these Lactobacillus and Bifidobacterium strains in families with a history of atopic disease significantly lowered the incidence of eczema in children [R, R, R, R, R, R, R, R, R, R, R, R].
Borage Oil
Filaggrin was observed to increase in amount in guinea pigs fed borage oil [R].
Borage oil contains high levels of omega-6 fatty acids (such as gamma linolenic acid) that are vital to the proper structure and function of the skin barrier [R].
In a few studies of children with seborrheic dermatitis, topical borage oil improved the symptoms within 1-3 weeks [R, R, R].
In children with eczema (atopic dermatitis), wearing undershirts coated with borage oil for 2 weeks improved their
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